Kayu Ular: Etnomedisin, Fitokimia, Aktivitas dan Toksisitas - Obat Tradisional Antimalaria Andalan Orang Timor
Keywords:
Strychnos ligustrina, Tumbuhan Obat, Obat Tradisional, Malaria, TimorSynopsis
Tumbuhan obat merupakan sumber yang sangat potensial untuk menghasilkan obat-obatan modern. Studi tentang pemanfaatan tumbuh-tumbuhan oleh masyarakat tradisional yang kemudian dilanjutkan dengan pemeriksaan fitokimia, uji pra-klinis dan uji klinis, merupakan pendekatan penting untuk menemukan dan mengembangkan obat obatan baru dari sumber obat tradisional. Kayu Ular (Strychnos ligustrina) adalah obat tradisional andalan masyarakat asli di Pulau Timor untuk mengobati penyakit malaria. Pamor tumbuhan ini sebagai obat antimalaria diketahui secara luas oleh masyarakat. Untuk mengembangkan Kayu Ular ini menjadi obat antimalaria modern, maka telah dilakukan beberapa penelitian ilmiah untuk menguji kembali apakah tumbuhan ini benar berkhasiat, mengandung senyawa aktif antimalaria, dan aman untuk dikonsumsi. Buku ini merupakan kompilasi dari serangkaian hasil penelitian yang telah penulis lakukan atas tumbuhan Kayu Ular ini, yang mencakup aspek pemanfaatan tumbuhan ini sebagai obat tradisional antimalaria oleh masyarakat asli di Pulau Timor (etnomedisin), pemeriksaan kandungan kimia, pengujian aktivitas antimalaria secara in vivo dan in vitro, dan pengujian toksisitas ekstrak tumbuhan Kayu Ular ini. Semoga buku ini dapat memperkaya pengetahuan pembaca sekalian tentang potensi dan keamanan tumbuhan Kayu Ular sebagai obat antimalaria, dan prospek pengembangan ekstrak atau senyawa aktif dari tumbuhan ini menjadi calon obat antimalaria yang baru.
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