Cancer Conundrum: The Etiology, Global Trends and National Response

Ika Nurlaila; Dwi Wahyu Indriati; Dwi Wahyu Indriani; Asri Sulfianti; Sri Ningsih

doi:10.55981/brin.1227

Cancer Conundrum: The Etiology, Global Trends and National Response

Authors

Ika Nurlaila, Research Center for Vaccine and Drugs, National Research and Innovation Agency (BRIN); Dwi Wahyu Indriati, Airlangga University; Dwi Wahyu Indriani, Research Center for Vaccine and Drugs, BRIN; Asri Sulfianti, Research Center for Vaccine and Drugs, BRIN; Sri Ningsih, Research Center for Pharmaceutical Ingredients and Traditional Medicine, BRIN

DOI: https://doi.org/10.55981/brin.1227

Keywords:

cancer, rare cancer, disparity, indonesia, intervention, aging

Synopsis

Cancer remains one of the most formidable public health challenges and the second leading cause of mortality worldwide. Beyond its intricate biological etiology and shifting global epidemiological patterns, the fight against cancer is complicated by profound disparities in healthcare access, diagnostic delays, and variable therapeutic responsiveness, particularly in developing nations such as Indonesia.

Cancer Conundrum: The Etiology, Global Trends, and National Response delivers a comprehensive exploration of carcinogenesis mechanisms-including the Warburg effect, cellular hallmarks of cancer, and tumor microenvironment dynamics-alongside conventional and cutting-edge therapeutic platforms such as gene therapy, oncolytic virotherapy, and immunotherapy. By bridging fundamental molecular oncology with Indonesia's national health landscape and clinical strategies, this book serves as a vital reference for researchers, healthcare professionals, oncologists, and policymakers committed to transforming cancer management.

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